3,087 reviewsof the Weight Doctors® Group · 97% recommendation rateBlog · 26 June 2026 · 7 min read

hydroGMA and endo sleeve: two techniques in one procedure

Less hunger and a smaller stomach – endoscopically, without an abdominal incision and in one appointment. How the combination of hydroGMA and Weight Doctors SLEEVE® works and what it can achieve.

GermanyMedically reviewed byPriv.-Doz. Dr. med. Dörte WichmannSpecialist in visceral surgery & expert in endobariatricsLast updated:

When the injection is too little and surgery is too much

Two gentle endoscopic techniques in one procedure – with a result that can come close to stomach reduction, entirely without surgery.

Many people with significant excess weight know the feeling of being caught between two options: GLP-⁠1 therapy has to be used regularly and often long term, while gastric sleeve surgery is a final surgical step. In between, there is a gap. This is exactly where a new path comes in: Weight Doctors® hydroGMA combined with Weight Doctors SLEEVE®.

Both procedures are performed endoscopically via a gastroscopy and can be carried out in one appointment – without an abdominal incision. hydroGMA dampens hunger, and Weight Doctors SLEEVE® reduces the stomach volume. Two principles of action that complement each other.

hydroGMA

What is hydroGMA – and why target hunger?

hydroGMA is a gentle endoscopic procedure. During a gastroscopy, the top layer of the mucosa of the gastric fundus is treated in a targeted way – exactly where the cells that produce ghrelin, the hunger hormone, are located. Less ghrelin means less hunger.

The idea behind it: anyone who constantly fights their own hunger rarely keeps it up. hydroGMA therefore targets the hormonal root of hunger – as a one-off procedure of around 30 minutes instead of a weekly injection. The effect does not set in immediately, but over a few weeks, while the body breaks down the hunger hormone already present.

  • Hormone switchThe treatment targets the mucosal cells of the gastric fundus that produce the hunger hormone ghrelin.
  • MethodDuring a gastroscopy, the top layer of the mucosa is treated gently – using the MOVIVA® system.
  • DurationThe procedure is usually carried out under brief sedation or short general anaesthesia and takes about 30 minutes.
  • EffectYou may feel full sooner and have less appetite; weight loss of up to 15% of starting weight is possible.
Advantages

The main advantages at a glance

  • No incisionsIt is not a surgical procedure – the anatomy of the stomach remains unchanged.
  • No foreign bodiesUnlike with the gastric balloon, nothing remains in the body after the procedure.
  • No long-term medicationno regular intake and no weekly injection.
  • Quick recoveryMost patients are back to everyday life the very next day.
  • RepeatableAs the hunger cells can grow back over the years, the procedure can be repeated if needed.
The combination

Two methods,
one procedure

Weight Doctors SLEEVE® reduces the stomach endoscopically from the inside – similar to conventional stomach reduction, but without an abdominal incision and without removing stomach tissue. It deliberately spares the upper part of the stomach, the gastric fundus.

That is exactly where hydroGMA works. Together they achieve what neither procedure achieves alone: a smaller stomach volume meets less hunger.

  • Two levers at the same timeless hunger and a smaller stomach.
  • One appointment, one procedureBoth steps take place during the same gastroscopy under general anaesthesia; hydroGMA extends the procedure by only about 30 minutes.
  • Without surgeryno external incision, no permanently removed tissue, short recovery.
  • Tailor-madeWhether alone or combined, we decide individually based on your starting weight and your goal.
In conversation

Our specialists explain hydroGMA

How the procedure works, what the combination offers and what the first experiences show is explained step by step in nine short films by Priv.-Doz. Dr. med. Dörte Wichmann and Dr. med. Oliver Scheffel – from the principle through the study evidence and the process to the combination with the endo sleeve.

“hydroGMA is endoscopic precision work: we treat only the top layer of the mucosa in a targeted way – exactly where the hunger cells are located. No incision, no stitches. For many patients, this is the gentle entry point they have long been waiting for.”

Priv.-Doz. Dr. med. Dörte Wichmann, specialist in visceral surgery & specialist in endobariatrics
Put into honest perspective

How much weight loss is possible?

First, the honest answer: in the treatment of severe excess weight, hydroGMA is a new technique and not yet an established standard procedure. So far, the following has been reported:

  • hydroGMA aloneweight loss of up to 15% of starting weight.
  • hydroGMA with Weight Doctors SLEEVE®more in combination – some data approach the magnitude of a conventional gastric sleeve operation.

These figures are promising, but in part not yet conclusively published. Results vary from person to person and depend heavily on diet and exercise. There is no guarantee – but a well-thought-out concept and close support can noticeably improve your chances.

Process

How the combined procedure works – and what comes afterwards

The basis is a gastroscopy. In the combined appointment, Weight Doctors SLEEVE® is placed first, and hydroGMA is then added in the gastric fundus.

  1. MarkThe area to be treated in the gastric fundus is marked.
  2. Place the cushionA protective saline cushion is injected under the mucosa.
  3. TreatThe top layer of the mucosa is treated gently.

After the combined procedure, most patients currently stay overnight for observation for safety reasons. Many report no pain, no nausea and no vomiting. As with any procedure, there are risks: a feeling of pressure in the upper abdomen, nausea or a sore throat are common and usually temporary; bleeding or infections are rare.

After the procedure

What matters is the time afterwards

For a lasting result, what happens after the procedure counts. That is why the treatment is always embedded in Weight Doctors® 360° nutrition coaching – with a food diary and personal support.

In comparison

Injection, balloon, combination or surgery

PathHow it worksWhat you should know
GLP-⁠1 therapyvia the feeling of fullness, entirely without a procedurehas to be used regularly and often long term; after stopping, the weight often comes back
Gastric balloona companion for a limited timeis removed again after 6 or 12 months
hydroGMA + Weight Doctors SLEEVE®two principles of action in a single proceduredesigned to be long-term, without surgery; nothing has to be removed or injected weekly
Gastric sleeve operationvery effectivefinal surgical procedure with incisions and a hospital stay

The advantage of the combination: it joins the sustainability of a one-off procedure with the avoidance of surgery – and targets hunger and stomach volume at the same time.

Consultation

Many paths – one consultation

At Weight Doctors®, our advice is independent of any one therapy. If another path suits your situation better, we will recommend exactly that. You decide – we listen first.

  • Weight Doctors® hydroGMALosing weight without medication – lowering the hunger hormone endoscopically, without surgery, alone or combined with Weight Doctors SLEEVE®; self-pay service.
  • Weight Doctors® GLP-⁠1Losing weight without a procedure, supported by specialists; self-pay service.
  • Weight Doctors® GASTRIC BALLOONa companion for a limited time for 6 or 12 months; self-pay service.
  • Weight Doctors SLEEVE®permanent stomach reduction without conventional surgery with pose® 3.0 Double Helix or OverStitch NXT™; chance of cost coverage by German health insurance where there is a medical indication in line with the guidelines.
  • Weight Doctors BARIATRICS®Gastric bypass or gastric sleeve surgery for higher BMIs, including private medical preliminary examination and aftercare; chance of cost coverage by German health insurance where there is a medical indication in line with the guidelines.
  • Weight Doctors® RESHAPEBody contouring after successful weight loss; chance of cost coverage by German health insurance where there is a medical indication in line with the guidelines.
  • Weight Doctors® REVISIONCorrective procedure if an earlier weight-loss operation has not brought the desired success; chance of cost coverage by German health insurance where there is a medical indication in line with the guidelines.

You can find the prices in the service overview. And if you are still unsure: that is exactly what the no-obligation consultation is for.

Treatment location

Consultation near you,
treatment in Wertheim

Weight Doctors® has 23 locations in 6 countries, 15 of them in Germany – from Aachen to Wiesbaden – as well as the Nationalklinik in Wertheim am Main as the national obesity centre.

We carry out hydroGMA at the Weight Doctors® Nationalklinik in Wertheim, about 40 minutes south of Frankfurt Airport. The no-obligation initial consultation is conveniently possible by telephone, by video or at a location near you. If you travel by air, our patient service will, on request, organise everything to do with your journey – including a shuttle from Frankfurt.

Our team speaks German, Dutch and English as native languages.

Films

  • What is hydroGMA? – Priv.-Doz. Dr. med. Dörte Wichmann and Dr. med. Oliver Scheffel
  • How hydroGMA works – Dr. med. Oliver Scheffel
  • What the studies show – Priv.-Doz. Dr. med. Dörte Wichmann
  • Gentler than a gastric balloon – Dr. med. Oliver Scheffel
  • Back to everyday life the very next day – Priv.-Doz. Dr. med. Dörte Wichmann
  • How much weight is possible? – Dr. med. Oliver Scheffel
  • The process – Priv.-Doz. Dr. med. Dörte Wichmann
  • Combined with the endo sleeve – Dr. med. Oliver Scheffel
  • Two techniques, one procedure – Priv.-Doz. Dr. med. Dörte Wichmann and Dr. med. Oliver Scheffel
Frequently asked questions

Questions and answers

Your question isn’t listed? Your specialist will take time for it during the consultation.

Can I have hydroGMA and Weight Doctors SLEEVE® in one procedure?

Yes. Both procedures are performed endoscopically via a gastroscopy and can be combined in one appointment under general anaesthesia: the stomach is reduced with Weight Doctors SLEEVE®, and hydroGMA is added in the area of the gastric fundus. This makes the procedure only about 30 minutes longer.

Is it surgery?

No. Both procedures are performed endoscopically via a gastroscopy – without external incisions and without permanently removing stomach tissue. It is a gentle, minimally invasive procedure, not conventional surgery.

How long do I have to stay in the clinic?

After the combined procedure, we currently usually keep patients overnight for observation for safety reasons. With growing experience, outpatient treatment is also conceivable in future.

What does hydroGMA cost, and does German health insurance pay for it?

hydroGMA is a purely self-pay service; the German statutory health insurers do not cover it. Viewed over a longer period, the one-off procedure can nevertheless be cheaper than a long-term weight-loss injection. Financing through medipay is possible; we discuss your cost framework in the consultation.

Who is the treatment not suitable for?

It may not be suitable, among other things, in cases of active stomach ulcers, severe clotting disorders, certain previous operations on the stomach, pregnancy or severe general illnesses. We always check this individually before the procedure.

Is the consultation really no obligation?

Yes, completely. We advise you on all paths – from GLP-⁠1 therapy and the gastric balloon to Weight Doctors SLEEVE® and hydroGMA – and recommend what suits your situation. Only when you decide on a path do we move forward.

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All treatments at a glance

Wide range of services
no procedure
Surgery
  1. No procedureWeight Doctors® GLP-⁠1 pharmacotherapyMedication-based, no procedure
  2. No procedureWeight Doctors® 360°Nutrition coaching
  3. Long-lastingNewWeight Doctors® hydroGMAEndoscopic, no incisions
  4. No surgeryWeight Doctors® GASTRIC BALLOONTemporary, also swallowable
  5. No surgeryHealth insurance cover also possible*Weight Doctors SLEEVE®Endoscopic, permanent
  6. With surgeryHealth insurance cover also possible*Weight Doctors BARIATRICS®Surgical, minimally invasive
  7. With surgeryHealth insurance cover also possible*Weight Doctors® REVISIONCorrective procedure after weight-loss surgery
  8. LipoedemaHealth insurance cover also possible*Weight Doctors® lipoedema surgeryLiposuction for lipoedema
  9. After weight lossHealth insurance cover also possible*Weight Doctors® RESHAPEAfter weight loss

* For patients with German statutory health insurance: if the medical indication is established in line with the DGAV guidelines, reimbursement may be possible.

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